2B or Not 2B: A Tail of Two NMDA Receptor Subunits
نویسندگان
چکیده
N-methyl-D-aspartate (NMDA) receptor activation can be neuroprotective or neurotoxic depending on receptor location. In this issue of Neuron, Martel et al. (2012) demonstrate that the C-terminal of NMDA receptor subunits also contributes critically to excitotoxicity. NMDA receptor subunits containing the GluN2B C-terminal are more lethal than those containing the GluN2A tails, regardless of location.
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ورودعنوان ژورنال:
- Neuron
دوره 74 شماره
صفحات -
تاریخ انتشار 2012